PubMed
Randomized controlled trial of oral glutathione supplementation on body stores of glutathione
Richie JP Jr, Nichenametla S, Neidig W, et al. Eur J Nutr. 2015
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Side-by-side observational reports from PeptIQ users. This compares self-reported patterns — not clinical head-to-head trials.
Last reviewed . By the PeptIQ team.
From check-in ratings — separate from side effects logged below. Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.
Favorable 98% · Mixed 2% · Unfavorable overall 0%
Benefits users selected when logging a favorable or mixed check-in.
Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.
Median bucket: 5+ mg · Most common: 5+ mg
Reports span 0.2 to ≥ 5 mg (open-ended top bucket)
Anonymized self-reports from PeptIQ users — not prescribing guidance. Buckets group similar logged amounts; open-ended top buckets mean “at least” that dose.
Among repeat reporters, 96% said they felt similar to their last entry, 4% more positive, and 0% more negative.
Overall, repeat reporters leaned more positive than their previous entry.
Median gap between entries: 66 days · Based on 26 repeat reporters
From check-in ratings — separate from side effects logged below. Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.
Favorable 99% · Mixed 1% · Unfavorable overall 0%
Benefits users selected when logging a favorable or mixed check-in.
Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.
Median bucket: 2–3 mg · Most common: 1–2 mg
Reports span 0 to ≥ 5 mg (open-ended top bucket)
Anonymized self-reports from PeptIQ users — not prescribing guidance. Buckets group similar logged amounts; open-ended top buckets mean “at least” that dose.
Among repeat reporters, 100% said they felt similar to their last entry, 0% more positive, and 0% more negative.
Overall, repeat reporters leaned similar or mixed compared to their previous entry.
Median gap between entries: 51 days · Based on 45 repeat reporters
Published sources linked on the Glutathione and Retatrutide wiki pages.
PubMed
Richie JP Jr, Nichenametla S, Neidig W, et al. Eur J Nutr. 2015
PubMed
Davids LM, van Wyk JC, Khumalo NP. S Afr Med J. 2016
PubMed
Liu JD, Liu WB, Zhang CY, et al. Fish & shellfish immunology. 2020
PubMed
Hsiao YF, Huang SC, Cheng SB, et al. International journal of molecular sciences. 2024
PubMed
Rosenstock J, Frias J, Jastreboff AM, et al. Lancet. 2023
PubMed
Jastreboff AM, Kaplan LM, Frias JP, et al. N Engl J Med. 2023
ClinicalTrials.gov
ClinicalTrials.gov. Clinical trial registry. 2024
ClinicalTrials.gov
ClinicalTrials.gov. Clinical trial registry. 2024
PubMed
Jastreboff AM, Kaplan LM, Frías JP, et al. The New England journal of medicine. 2023
PubMed
Katsi V, Koutsopoulos G, Fragoulis C, et al. Biomolecules. 2025