Peptides researched for
Anxiety / stress
Feeling calmer under stress
2 peptides · 4 studies
What people research this for
Most people who look this up want to feel calmer and handle stress better. Two peptides, Selank and Semax, have been studied for that. The research is small and early, and it does not replace proven anxiety care.
Researched for
- Everyday stress
- Feeling anxious
- Staying calm
What the studies say so far
Selank has reviews describing how it might act on the brain's calming signals. A brain imaging study gave Selank and Semax to healthy volunteers and looked at changes in the brain at rest. Studies in rodents looked at memory after alcohol exposure. There are very few controlled trials in people with anxiety, far fewer than for approved anxiety medicines.
Peptides studied
Each peptide below has been studied in this area. The label shows how far that research has gone.
Selank
Small early studies in peopleResearch review · 3 studies
Study note. Selank has molecular anxiolytic reviews, human connectomic imaging, and rodent BDNF/memory papers, not a guideline first-line anxiolytic.
- Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity. (opens in a new tab)
Vyunova TV, Andreeva L, Shevchenko K · Protein and peptide letters · 2018 · PubMed
- Functional Connectomic Approach to Studying Selank and Semax Effects. (opens in a new tab)
Panikratova YR, Lebedeva IS, Sokolov OY · Doklady biological sciences · 2020 · PubMed
- Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats. (opens in a new tab)
Kolik LG, Nadorova AV, Antipova TA · Bulletin of experimental biology and medicine · 2019 · PubMed
- Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity. (opens in a new tab)
Semax
Small early studies in peopleObservational study in people · 1 study
Study note. Semax studied alongside Selank in resting-state network imaging of healthy volunteers.
- Functional Connectomic Approach to Studying Selank and Semax Effects. (opens in a new tab)
Panikratova YR, Lebedeva IS, Sokolov OY · Doklady biological sciences · 2020 · PubMed
- Functional Connectomic Approach to Studying Selank and Semax Effects. (opens in a new tab)
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