PubMed
Thymosin beta4: a multi-functional regenerative peptide (review)
Goldstein et al., 2012
Healing & RecoveryResearch OnlyC
TB-500 Fragment
TB4 Fragment
TB4-derived fragment used in repair protocols; limited direct human data.
Observational report only — live community data. Not medical advice. Does not recommend doses, protocols, or treatments.
- Studies cited
- 4
- Research grade
- C
- Experience
- 56
- Activity
- 84
Overall check-ins
Trackers & reports
Overview
About TB-500 Fragment
TB4-derived fragment used in repair protocols; limited direct human data.
- Category
- Healing & Recovery
- Regulatory status
- Research Only
- Also known as
- TB4 Fragment
- Self-reports
- 26
Community
What 26 users report
26 community reports
Overall experience
From check-in ratings — separate from side effects logged below. Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.
Favorable 3% · Mixed 97% · Unfavorable overall 0%
Most reported benefits
Benefits users selected when logging a favorable or mixed check-in.
Recovery
176
Most logged side effects
Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.
Injection site irritation
171
Self-reported dose per injection
Median bucket: 2+ mg · Most common: 2+ mg
Reports span 1 to ≥ 2 mg (open-ended top bucket)
1–2 mg
59
2+ mg
117
Anonymized self-reports from PeptIQ users — not prescribing guidance. Buckets group similar logged amounts; open-ended top buckets mean “at least” that dose.
Commonly stacked with
How repeat users are trending
Among repeat reporters, 79% said they felt similar to their last entry, 21% more positive, and 0% more negative.
Overall, repeat reporters leaned more positive than their previous entry.
Median gap between entries: 188 days · Based on 24 repeat reporters
Research
Cited research (3)
Source
PubMed
Thymosin beta 4 and wound healing: a multifunctional peptide
Goldstein et al., 2010
PubMed
Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance
Mendias et al., 2026
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Frequently asked
What do PeptIQ users report about TB-500 Fragment?
This page summarizes 26 anonymized self-reports from PeptIQ users who track TB-500 Fragment, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
How do side effects relate to overall experience for TB-500 Fragment?
PeptIQ separates overall check-in ratings (favorable, mixed, or unfavorable) from logged side effects like nausea or fatigue. Users often report benefits and side effects in the same check-in — a high experience score does not mean zero side effects were noted.
What research is cited for TB-500 Fragment?
3 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
Is TB-500 Fragment safe to use?
This wiki does not assess safety or recommend use. TB-500 Fragment is listed as Research Only. Consult a licensed clinician for personal medical decisions.
What are the purported benefits and uses of TB-500 Fragment?
Research, primarily in animal models, suggests TB-500 Fragment may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
SourceWhat is the legal status of TB-500 Fragment?
TB-500 Fragment is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified TB-500 Fragment as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceWhat are the known or theoretical side effects and risks of TB-500 Fragment?
The safety and effectiveness of TB-500 Fragment have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhat is the current state of research on TB-500 Fragment?
While there are over 200 published studies on TB-500 Fragment, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source