ce to know we asked for questions from the subscribers and we got a lot of questions about recovery from injury i thought there would be some useful things we could mention maybe it would help antoine also one of the interesting things i came across in research is that beta blockers used either before a surgery or after a surgery dramatically improve recovery dramatically there's a tremendous amount of evidence about this basically showing you that adrenaline and sympathetic nervous drive remember your nervous system has a parasympathetic nervous drive and a sympathetic the sympathetic is not sympathetic it's fight or flight that fight or flight nervous drive hampers your recovery from surgery does it do the same when you work out we're not totally sure i think that taking beta blockers after your workout may improve your recovery yes yes it is right yeah it does that's something we should focus also yeah tell me myself myself and my client so i got a lot of clients now on the vivolo which was also one of the questions and their recovery improves is it is it a little bit conducive to fat loss yes absolutely but you know when you want the most amount of recovery during the off season yeah right no no it's a fat gain yeah so you gain a little bit more fat but it also prevents or it also lowers the caloric requirements because your heart rate is lower and you're not in this fight or flight state all the time you know or you calm down faster post-workout so a lot of my clients run five milligrams in a vivaldo right now and then you know most of my clients don't get injuries because i always i was hammering them listen collagen and gelatin protein instead of the whey protein because it has building blocks for connective tissue and i hammer it in all these guys stop the whey protein switch the collagen and gelatin and add half a scoop of whey protein for flavoring that's it and it makes it work that's not about a world of difference a world of different world of difference is relevant but as like comparable i guess was i remember i was looking at recovery modalities for burn victims in terms of in like a hyper catabolic state with high sympathetic drive presumably their adrenaline going crazy and propranolol was like one of the top therapies to intervene i was it was like anavar like test or something and then it was like propranolol i was like huh interesting i need to calm the whole body down systemically and then beta blockers are one of the ways to do it how much it would contribute to collagen synthesis i'm not really sure but i think it just down regulates all the stress responses and the inflammatory responses it's used in burn burn victims even in cardiac surgeries it improves recovery improves not only recovery but survival from the surgeries i mean it's tremendous the other thing i want to mention the main principle something antoine did last time i remember hearing his video he used bpc157 and tb500 if i recall correctly what's that for angiogenesis the birth of new blood vessels if you can get blood to the injured area blood brings your natural growth factors in your body not just growth hormone fibroblasts growth factor transforming growth factor not a great thing a lot of other growth factors vascular endothelial growth factor which promotes angiogenesis so you really want more blood vessels now generally do you want a lot of blood vessels no because angiogenesis promotes cancer formation that's the big fear it's one of the reasons you don't take growth hormone all that all you're on well steve does but not all of us take a little bit he takes a little he likes growth hormone but he's a little bit even i don't yeah but if i had if i had what happened uh to antoine happened to me i might consider it for a short period in fact i'm considering it for my own finger right now even though i'm scared to death of growth hormone but the angiogenesis is really interesting now i don't understand the compounds bpc and one and tb that well i haven't studied them that well but i know a lot about erythropoietin i studied that a lot i'm very interested in erythropoietin peptides by the way if anyone watches this and you're an entrepreneurial person try to make it on urethropoietin peptide you can go to my blog and figure out how to they're not all patented and what's interesting about them you can get a peptide where you don't get erythropoietis you don't get more red blood cells so your blood doesn't thicken and you don't have to dump your blood out but erythropoietin has tremendous angiogenesis properties through the jack stat pathway so that's one thing also it also acts as a separate growth factor for anabolism i believe and whether that's indirect from the red blood cells or the uh epo itself your erythropoietin so like if you want to recover an injury there will be a temporary period with the tb500 the bpc and and perhaps anavar to promote a lot of collagen synthesis but at the efficacious dose 10 milligrams 20 milligrams not the you know burn victim dose of 180 to 240 milligrams per day oh they take that much huh yeah wow we should talk more about anavar we'll talk more about anavar when we get to pre-workouts later it's an interesting subject but another thing i want to mention is growth factors what do growth factors do in the body everybody thinks about growth factors splitting our cells up they do other things also growth factors and there's something i talked to derek about because i'm interested also in the process of hair loss and whether minoxidil can actually prevent because it's thought not to prevent hairs from from dying but i find it hard to believe that having more growth factors from blood in the scalp around the hairs can't in some small way prevent the hairs from dying maybe not a very obvious way generally in the body in the brain i know very well growth factors brain derived neurotrophic factor all growth factors nerve growth factors protect cells from apoptosis from death so when you get an injury if you have higher growth hormone levels you'll get less cells dying not just cells dividing so two different things and you can get the growth factor from growth hormone or you could get your blood as we said earlier closer to the area which is why right now i've injured my hand twice or three i'm trying to do it three times a day but twice a day i'm putting my hand in ice water and then in hot water ice water hot water repeatedly and then getting the blood in there because that's the key factor you know and the final thing is our our question from the audience was actually about mk677 the guy was asking should somebody use mk677 if they do a surgery to recover from the surgery i think that mk677 is not really what you want that's a ghrelin mimetic ghrelin is a stress hormone ghrelin will turn on your sympathetic nervous drive if you're not using beta blockers and all that you're putting yourself in a stress state i use mk677 to upregulate dopamine in the brain because of the sympathetic nervous drive growth hormone is separate from ghrelin we need to start thinking of mk677 as ghrelin ghrelin does produce growth hormone but it also produces ghrelin what do you guys think that's like that's a good point because i was at first i was thinking logically well like as far as like differentiating the different impacts of gh inherently versus the downstream igf-1 like in terms of injury recovery what is it mainly the girl factor one that's going to be inducing the properties you want in a recovery aspect rather than the like obviously from a gh aspect and you think of lipolysis that's more from the gh parent compound right versus the igf-1 so my thought process before getting into which is more responsible for the recovery um i was thinking for you because you don't want your igf-1 severely elevated mk is like from what i've seen personally disproportionately good at raising like your gh levels versus your igf-1 so the igf-1 elevation is not that significant but the gh you get i personally noticed my hair grows much faster on mk677 than on a high dose even of high quality gh so yeah most every single person i've talked to that compares the two notices the same thing but your igf-1 on paper will be much lower it'll be within the therapeutic reference range all but at the top end so i have a little secret for you my igf-1 receptors don't work so it doesn't matter no i'm deficient i could have as much as i want so i was thinking hypothetically if it mattered you would want to keep your if you want to keep your igf-1 lower for whatever reason the mk might make sense because the actual gh properties i do find at least in some context when it comes to the the fountain of youth qualities you commonly hear about like the hair growth i noticed it more profoundly from mk however the ghrelin aspect totally forgot even though i literally wrote an article on it about how it causes like literally can induce ptsd type like symptoms essentially and at least in rodents it was used in like that fear fear model or whatever it was to induce like literally induce ptsd in them so for uh somebody trying to recover from anything obviously it's probably not an ideal choice anything that leverages ghrelin specifically so i would agree entirely on avoiding it do you think also the the water retention and the potential for insulin resistance would be kind of counterintuitive to recover a particular injury because if you're you know if you get additional water retention and this uh insulin resistance then a lot of the nutrients are not going to end up in the yeah the mk seems disproportionately bad in terms of getting you insulin resistant quickly you don't have to inject so it's easy well because it thinks you're hungry it thinks you're starving that's what happens when you're fast the first two days are the fast that's empty like you guys don't worry about the glp-1 agonism and chronically like releasing insulin from that