PubMed
Acetyl hexapeptide-3 in a emulsion formulation for reduced wrinkle depth
Raikou et al., 2009
Skin & AestheticsOTC CosmeticB
SNAP-8
Acetyl Octapeptide-3
Topical cosmetic peptide used in anti-wrinkle formulations.
Observational report only — live community data. Not medical advice. Does not recommend doses, protocols, or treatments.
- Studies cited
- 4
- Research grade
- B
- Experience
- 55
- Activity
- 71
Overall check-ins
Trackers & reports
Overview
About SNAP-8
Topical cosmetic peptide used in anti-wrinkle formulations.
- Category
- Skin & Aesthetics
- Regulatory status
- OTC Cosmetic
- Also known as
- Acetyl Octapeptide-3
- Self-reports
- 6
Community
What 6 users report
6 community reports
Overall experience
From check-in ratings — separate from side effects logged below. Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.
Favorable 0% · Mixed 100% · Unfavorable overall 0%
Most reported benefits
Benefits users selected when logging a favorable or mixed check-in.
Energy
6
Mood
6
Most logged side effects
Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.
Injection site irritation
6
Self-reported dose per injection
Median bucket: 0–25 mcg · Most common: 0–25 mcg
Reports cluster around 0–25 mcg
0–25
6
Anonymized self-reports from PeptIQ users — not prescribing guidance. Buckets group similar logged amounts; open-ended top buckets mean “at least” that dose.
Commonly stacked with
Research
Cited research (3)
Source
PubMed
Targeting lymphoid-derived IL-17 signaling to delay skin aging
Solá et al., 2023
PubMed
Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair
Shook et al., 2018
Tools
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Frequently asked
What do PeptIQ users report about SNAP-8?
This page summarizes 6 anonymized self-reports from PeptIQ users who track SNAP-8, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
How do side effects relate to overall experience for SNAP-8?
PeptIQ separates overall check-in ratings (favorable, mixed, or unfavorable) from logged side effects like nausea or fatigue. Users often report benefits and side effects in the same check-in — a high experience score does not mean zero side effects were noted.
What research is cited for SNAP-8?
3 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
Is SNAP-8 safe to use?
This wiki does not assess safety or recommend use. SNAP-8 is listed as OTC Cosmetic. Consult a licensed clinician for personal medical decisions.
What are the purported benefits and uses of SNAP-8?
Research, primarily in animal models, suggests SNAP-8 may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
SourceWhat is the legal status of SNAP-8?
SNAP-8 is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified SNAP-8 as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceWhat are the known or theoretical side effects and risks of SNAP-8?
The safety and effectiveness of SNAP-8 have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhat is the current state of research on SNAP-8?
While there are over 200 published studies on SNAP-8, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source