PubMed
Cerebrolysin for acute ischemic stroke (review)
Chen et al., 2017
FPE 1070
Cerebrolysin (FPE 1070) is a porcine brain-derived neuropeptide preparation containing a mixture of neurotrophic peptide fractions including BDNF-, NGF-, CNTF-, and GDNF-like fragments (<10kDa). Approved in Austria, Russia, China, South Korea, and other countries for Alzheimer's disease, post-stroke recovery, and traumatic brain injury. Multiple randomized controlled trials have demonstrated cognitive and functional improvements. Not FDA-approved in the US.
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Overview
Cerebrolysin (FPE 1070) is a porcine brain-derived neuropeptide preparation containing a mixture of neurotrophic peptide fractions including BDNF-, NGF-, CNTF-, and GDNF-like fragments (<10kDa). Approved in Austria, Russia, China, South Korea, and other countries for Alzheimer's disease, post-stroke recovery, and traumatic brain injury. Multiple randomized controlled trials have demonstrated cognitive and functional improvements. Not FDA-approved in the US.
Community
From check-in ratings — separate from side effects logged below. Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.
Favorable 100% · Mixed 0% · Unfavorable overall 0%
Benefits users selected when logging a favorable or mixed check-in.
Median bucket: 0–25 mcg · Most common: 0–25 mcg
Reports span 0–50 mcg
Anonymized self-reports from PeptIQ users — not prescribing guidance. Buckets group similar logged amounts; open-ended top buckets mean “at least” that dose.
Research
PubMed
Chen et al., 2017
PubMed
Ziganshina et al., 2023
PubMed
Ziganshina et al., 2017
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This page summarizes 6 anonymized self-reports from PeptIQ users who track Cerebrolysin, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
PeptIQ separates overall check-in ratings (favorable, mixed, or unfavorable) from logged side effects like nausea or fatigue. Users often report benefits and side effects in the same check-in — a high experience score does not mean zero side effects were noted.
3 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
This wiki does not assess safety or recommend use. Cerebrolysin is listed as Intl. Approved. Consult a licensed clinician for personal medical decisions.
Research, primarily in animal models, suggests Cerebrolysin may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
SourceCerebrolysin is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified Cerebrolysin as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceThe safety and effectiveness of Cerebrolysin have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhile there are over 200 published studies on Cerebrolysin, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source